Papers on Pichia Expression during Fermentation
- Carnicer M, Pierich AT, Dam JV, Heijnen JJ, Albiol J, Gulik WV, Ferrer P. Quantitative metabolomics analysis of amino acid metabolism in recombinant pichia pastoris under different oxygen availability conditions. Microb Cell Fact. 2012 Jun 15;11(1):83. [Epub ahead of print] PubMed PMID: 22704468.
- Zalai D, Dietzsch C, Herwig C, Spadiut O. A dynamic fed batch strategy for a Pichia pastoris mixed feed system to increase process understanding. Biotechnol Prog. 2012 May;28(3):878-86. doi: 10.1002/btpr.1551. Epub 2012 May 21. PMID: 22505140
- Singh S, Gras A, Fiez-Vandal C, Martinez M, Wagner R, Byrne B. Large-scale production of membrane proteins in Pichia pastoris: the production of G protein-coupled receptors as a case study. Methods Mol Biol. 2012;866:197-207. PMID: 22454125
- Baumann K, Adelantado N, Lang C, Mattanovich D, Ferrer P. Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris. Microb Cell Fact. 2011 Nov 3;10:93. PubMed PMID: 22050768; PubMed Central PMCID: PMC3219557.
- Wu D, Chu J, Hao YY, Wang YH, Zhuang YP, Zhang SL. Incomplete protein disulphide bond conformation and decreased protein expression result from high cell growth during heterologous protein expression in Pichia pastoris. J Biotechnol. 2012 Jan;157(1):107-12. Epub 2011 Sep 8. PubMed PMID: 21924302.
- Fricke J, Pohlmann K, Tatge F, Lang R, Faber B, Luttmann R. A multi-bioreactor system for optimal production of malaria vaccines with Pichia pastoris. Biotechnol J. 2011 Apr;6(4):437-51. doi: 10.1002/biot.201000385. PubMed PMID: 21472987.
- Jacobs PP, Inan M, Festjens N, Haustraete J, Van Hecke A, Contreras R, Meagher MM, Callewaert N. Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate. Microb Cell Fact. 2010 Nov 23;9:93. PubMed PMID: 21092289; PubMed Central PMCID: PMC3004841.
- Baumann K, Carnicer M, Dragosits M, Graf AB, Stadlmann J, Jouhten P, Maaheimo H, Gasser B, Albiol J, Mattanovich D, Ferrer P. A multi-level study of recombinant Pichia pastoris in different oxygen conditions. BMC Syst Biol. 2010 Oct 22;4:141. PubMed PMID: 20969759; PubMed Central PMCID: PMC2987880.
- Holmes WJ, Darby RA, Wilks MD, Smith R, Bill RM. Developing a scalable model of recombinant protein yield from Pichia pastoris: the influence of culture conditions, biomass and induction regime. Microb Cell Fact. 2009 Jul 1;8:35. PubMed PMID: 19570229; PubMed Central PMCID: PMC2717918.
- Mattanovich D, Graf A, Stadlmann J, Dragosits M, Redl A, Maurer M, Kleinheinz M, Sauer M, Altmann F, Gasser B. Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris. Microb Cell Fact. 2009 Jun 2;8:29. PubMed PMID: 19490607; PubMed Central PMCID: PMC2702363.
- Tolner B, Smith L, Begent RH, Chester KA. Production of recombinant protein in Pichia pastoris by fermentation. Nat Protoc. 2006;1(2):1006-21. PubMed PMID: 17406338